The Marine Toxins Test Kits permit the qualitative and quantitative identification of marine toxic substances. These harmful chemicals are created by microscopic algae cells that reside in lakes, oceans and occasionally freshwater. These harmful chemicals may accumulate and cause illnesses in shellfish, seafood, and other food items.Marine toxins can have a significant impact on the industry of seafood. They can lead to a negative perception among the public about shellfish, health issues that are associated with it, and even directly affecting economic loss. Toxics are also responsible for millions of food-borne diseases every year. The presence of marine toxins can be detected using the LC/MS/MS. These tests are labor intensive and costly, and require a significant amount of technical expertise. A lot of laboratories continue to use rapid test kits (ELISAs or LFAs) to aid in the identification and detection of the toxic substances. The kits haven't been evaluated in a systematic manner.The poisoning of shellfish is caused by Diarrhetic Shellfish Toxins that are created in Dinophysis dinoflagellates. It is essential to identify DSTs to safeguard the global supply of seafood, protect public health, and encourage the expansion of the industry. The current methods for their detection aren't reliable. We evaluated the results of LCMS/MS, LCMS/LCTOX, and five commercially accessible rapid tests of shellfish that were contaminated naturally and with samples. They included Blue Mussels, Mytilus Galloprovincialis and Pipis.Toxins were measured by contract laboratories using a mixture of DST analogs: OA 35 uL/3 g (10 LOR of 0.1mg/kg) and the DTX-1 7.5 3 g, and the DTX-2 5.5 3 grams. The recovery of toxin was calculated and compared to the levels of toxin and spiked concentrations of CRM, a certified reference material (OA/DTX-1/DTX-2) and across labs.The four ELISAs gave false positive results if the spiked OA was close to or over the limits of regulation. The Abraxis PP2A ELISA as and the EuroProxima ELISA also gave a large number of false positive results when the OA concentration spiked was within or over the limit set by regulation.The tests using lateral flow were more successful than ELISA tests. All of the lateral flow tests, however, showed low reactivity for DSP congeners, which are known to be detected at very high levels in shellfish samples that are naturally contaminated. Milk Test kits includes DTX-2, GTX-1, and the DTX-3 (due the fact that they require hydrolysis before they release their ester forms). Abraxis PP2A ELISA revealed an extremely low reactivity to the DSP congener DTX-3.